Publications 

Osteoarthritis Initiative

(updated 6/17/14)

2014

 

1.    Alizai H, Virayavanich W, Joseph GB, Nardo L, Liu F, Liebl H, Nevitt MC, Lynch JA, McCulloch CE, Link TM. Cartilage Lesion Score: Comparison of a Quantitative Assessment Score with Established Semiquantitative MR Scoring Systems. Radiology.2014 Jan 16. [Epub ahead of print].

 

2.    Bloecker K, Guermazi A, Wirth W, Kwoh CK, Resch H, Hunter DJ, Eckstein F; OAI investigators. Correlation of semiquantitative vs quantitative MRI meniscus measures in osteoarthritic knees: results from the Osteoarthritis Initiative. Skeletal Radiol. 2014 Feb;43(2):227-32. Epub 2013 Nov 21.

 

3.    Bruns K, Svensson F, Turkiewicz A, Wirth W, Guermazi A, Eckstein F, Englund M. Meniscus body position and its change over four years in asymptomatic adults: a cohort study using data from the Osteoarthritis Initiative (OAI). BMC Musculoskelet Disord. 2014 Feb 5;15:32.[PMC3924236].

 

4.    Collins JE, Katz JN, Dervan EE, Losina E. Trajectories and risk profiles of pain in persons with radiographic, symptomatic knee osteoarthritis: data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2014 Mar 21. S1063-4584(14)01010-3.  [Epub ahead of print].

 

5.    Driban JB, Eaton CB, Lo GH, Ward RJ, Lu B, McAlindon TE. Knee injuries are associated with accelerated knee osteoarthritis progression: Data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2014 Apr 29. [Epub ahead of print].

 

6.    Dunlop DD, Song J, Semanik PA, Sharma L, Bathon JM, Eaton CB, Hochberg MC,  Jackson RD, Kwoh CK, Mysiw WJ, Nevitt MC, Chang RW. Relation of physical activity time to incident disability in community dwelling adults with or at risk of knee arthritis: prospective cohort study. BMJ. 2014 Apr 29;348:g2472.[PMC4004786].

 

7.    Duryea J, Iranpour-Boroujeni T, Collins JE, Vanwynngaarden C, Guermazi A, Katz JN, Losina E, Russell R, Ratzlaff C. Local-area cartilage segmentation (LACS), A semi-automated novel method of measuring cartilage loss in knee osteoarthritis.

Arthritis Care Res (Hoboken). 2014 Mar 24. [Epub ahead of print].

 

8.    Eckstein F, Boudreau RM, Wang Z, Hannon MJ, Wirth W, Cotofana S, Guermazi A, Roemer F, Nevitt M, John MR, Ladel C, Sharma L, Hunter DJ, Kwoh CK; for the OAI investigators. Trajectory of Cartilage Loss within Four Years of Knee Replacement- A Nested Case-Control Study from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2014 Apr 29. S1063-4584(14)01054-1. [Epub ahead of print].

 

9.    Everhart JS, Siston RA, Flanigan DC. Tibiofemoral subchondral surface ratio(SSR) is a predictor of osteoarthritis symptoms and radiographic progression: data from the Osteoarthritis Initiative (OAI). Osteoarthritis Cartilage. 2014 Apr

15. S1063-4584(14)01038-3. [Epub ahead of print].

 

10.  Hunter DJ, Nevitt M, Losina E, Kraus V. Biomarkers for osteoarthritis: Current position and steps towards further validation. Best Pract Res Clin Rheumatol. 2014 Feb;28(1):61-71.[PMC4010869].

 

11.  Kahn TL, Soheili AC, Schwarzkopf R. Poor WOMAC Scores in Contralateral Knee Negatively Impact TKA Outcomes: Data From the Osteoarthritis Initiative. J Arthroplasty. 2014 Mar 29. S0883-5403(14)00219-8. [Epub ahead of print].

 

12.  Laslett LL, Kingsbury SR, Hensor EM, Bowes MA, Conaghan PG. Effect of bisphosphonate use in patients with symptomatic and radiographic knee osteoarthritis: data from the Osteoarthritis Initiative. Ann Rheum Dis. 2014 May;73(5):824-830. Epub 2013 Apr 12.

 

13.  Liebl H, Joseph G, Nevitt MC, Singh N, Heilmeier U, Karupppasamy S, Jungmann PM, McCulloch CE, Lynch JA, Lane NE, Link TM. Early T2 changes predict onset of radiographic knee osteoarthritis: data from the osteoarthritis initiative. Ann Rheum Dis. 2014 Mar 10. [Epub ahead of print].

 

14.  Lindner C, Wallis GA, Cootes TF. Increasing shape modelling accuracy by adjusting for subject positioning: an application to the analysis of radiographic proximal femur symmetry using data from the Osteoarthritis Initiative. Bone. 2014

 

15.  Lu B, Driban JB, Duryea J, McAlindon T, Lapane KL, Eaton CB. Milk consumption and progression of medial tibiofemoral knee osteoarthritis: Data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2014 Apr 7. [Epub ahead of print].

 

16.  Ruhdorfer A, Wirth W, Hitzl W, Nevitt M, Eckstein F; for the OAI investigators. Thigh muscle strength is associated with knee symptoms but notwith radiographic disease stage of osteoarthritis - data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2014 Feb 27. [Epub ahead of print].

 

17.  Serebrakian AT, Poulos T, Liebl H, Joseph GB, Lai A, Nevitt MC, Lynch JA, McCulloch CE, Link TM. Weight loss over 48 months is associated with reduced progression of cartilage T2 relaxation time values: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2014 Apr 4. [Epub ahead of print].

 

18.  Sharma L, Chmiel JS, Almagor O, Dunlop D, Guermazi A, Bathon J, Eaton C, Hochberg M, Jackson R, Kwoh K, Mysiw WJ, Crema M, Roemer F, Nevitt M. Significance of pre-radiographic MRI lesions in persons at higher risk for knee osteoarthritis. Arthritis Rheumatol. 2014 Mar 12. [Epub ahead of print].

 

19.  Wirth W, Nevitt M, Hellio Le Graverand MP, Lynch J, Maschek S, Hudelmaier M, Eckstein F; OA Initiative Investigators Group. Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment - data from the Osteoarthritis Initiative.

Osteoarthritis Cartilage. 2014 Jan;22(1):63-70. Epub 2013 Nov 1.

 

20.  Zhang KY, Kedgley AE, Donoghue CR, Rueckert D, Bull AM. The relationship between lateral meniscus shape and joint contact parameters in the knee: a study using data from the Osteoarthritis Initiative. Arthritis Res Ther. 2014 Jan

28;16(1):R27. [PMC3978753]. [Epub ahead of print].

 

2013

 

21.  Alschuler KN, Molton IR, Jensen MP, Riddle DL. Prognostic value of coping strategies in a community-based sample of persons with chronic symptomatic knee osteoarthritis. Pain. 2013 Aug 19. [Epub ahead of print].

 

22.  Baum T, Joseph GB, Nardo L, Virayavanich W, Arulanandan A, Alizai H, Carballido-Gamio J, Nevitt MC, Lynch J, McCulloch C E, Link TM. Correlation of magnetic resonance imaging-based knee cartilage T2 measurements and focal knee lesions with body mass index: thirty-six-month followup data from a longitudinal, observational multicenter study. Arthritis Care Res (Hoboken). 2013;65:23-33.[PMC3432679].

 

23.  Badlani JT, Borrero C, Golla S, Harner CD, Irrgang JJ. The effects of meniscus injury on the development of knee osteoarthritis: data from the osteoarthritis initiative. Am J Sports Med. 2013 Jun;41(6):1238-44.

 

24.  Binks DA, Gravallese EM, Bergin D, Hodgson RJ, Tan AL, Matzelle MM, McGonagle D, Radjenovic A. Role of vascular channels as a novel mechanism for subchondral bone damage at cruciate ligament entheses in osteoarthritis and inflammatory arthritis. Ann Rheum Dis. 2013 Oct 4. [Epub ahead of print].

 

25.  Bloecker K, Guermazi A, Wirth W, Benichou O, Kwoh CK, Hunter DJ, Englund M, Resch H, Eckstein F; OAI investigators. Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing - data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2013;21:419-427.

 

26.  Bloecker K, Wirth W, Hunter DJ, Duryea J, Guermazi A, Kwoh CK, Resch H, Eckstein F. Contribution of regional 3D meniscus and cartilage morphometry by MRI to joint space width in fixed flexion knee radiography--a between-knee comparison in subjects with unilateral joint space narrowing.  Eur J Radiol. 2013 Dec;82(12). Epub 2013 Sep 16.

 

27.  Bowes MA, Vincent GR, Wolstenholme CB, Conaghan PG. A novel method for bone area measurement provides new insights into osteoarthritis and its progression. Ann Rheum Dis. 2013 Dec 4. [Epub ahead of print].

 

28.  Buck RJ, Wirth W, Dreher D, Nevitt M, Eckstein F.  Frequency and spatial distribution of cartilage thickness change in knee osteoarthritis and its relation to clinical and radiographic covariates - data from the osteoarthritis initiative.  Osteoarthritis Cartilage. 2013;21:102-109.

 

29.  Chuah TK, Reeth EV, Sheah K, Poh CL, Texture analysis of bone marrow in knee MRI for classification of subjects with bone marrow lesion - Data from the Osteoarthritis Initiative. Magn Reson Imaging. 2013;31(6):930-938.

 

30.  Chundru R, Baum T, Nardo L, Nevitt MC, Lynch J, McCulloch CE, Link TM. Focal knee lesions in knee pairs of asymptomatic and symptomatic subjects with OA risk factors - Data from the Osteoarthritis Initiative. Eur J Radiol. 2013;82(8):367-373.[PMC3696431].

 

31.  Colbert CJ, Almagor O, Chmiel JS, Song J, Dunlop D, Hayes KW, Sharma L.  Excess body weight and 4-year function outcomes: Comparison of african-americans and caucasians in the osteoarthritis initiative.  Arthritis Care Res (Hoboken). 2013;65:5-14. [PMC3514654].

 

32.  Cotofana S, Buck R, Dreher D, Wirth W, Roemer F, Duryea J, Nevitt M, Eckstein F; for the Osteoarthritis Initiative Investigators. Longitudinal (1-year) change in cartilage thickness in knees with early knee osteoarthritis: A within-person between-knee comparison-data from the OAI. Arthritis Care Res (Hoboken). 2013 Sep 19. [Epub ahead of print].

 

33.  Cotofana S, Wyman BT, Benichou O, Dreher D, Nevitt M, Gardiner J, Wirth W, Hitzl W, Kwoh CK, Eckstein F, Frobell RB; OAI Investigators Group. Relationship between knee pain and the presence, location, size and phenotype of femorotibial denuded areas of subchondral bone as visualized by MRI. Osteoarthritis Cartilage 2013 Sep;21(9):1214-22.

 

34.  Dannhauer T, Sattler M, Wirth W, Hunter DJ, Kwoh CK, Eckstein F. Longitudinal sensitivity to change of MRI-based muscle cross-sectional area versus isometric strength analysis in osteoarthritic knees with and without structural progression: pilot data from the Osteoarthritis Initiative. MAGMA. 2013 Nov 22. [Epub ahead of print]

 

35.  Dardzinski BJ, Schneider E. Radiofrequency (RF) coil impacts the value and reproducibility of cartilage spin-spin (T2) relaxation time measurements. Osteoarthritis Cartilage. 2013 May;21(5):710-20. Epub 2013 Jan 31.[PMC3624070].

 

36.  Dodin P, Abram F, Pelletier JP, Martel-Pelletier J. A fully automated system for quantification of knee bone marrow lesions using MRI and the Osteoarthritis Initiative (OAI) cohort (public datasets). J Biomed Graph Comput. 2013;3:51-65.

 

37.  Driban JB, Lo GH, Price L, Pang J, Miller E, Ward RJ, Hunter DJ, Eaton CB, Lynch JA, McAlindon TE; OAI Investigators Group. Bone marrow lesion volume reduction is not associated with improvement of other periarticular bone measures: data from the Osteoarthritis Initiative. Arthritis Res Ther. 2013;15(5):R153.[PMC3978480].

 

38.  Driban JB, Price L, Lo GH, Pang J, Hunter DJ, Miller E, Ward RJ, Eaton CB, Lynch JA, McAlindon TE. Evaluation of bone marrow lesion volume as a knee osteoarthritis biomarker--longitudinal relationships with pain and structural changes: data from the Osteoarthritis Initiative. Arthritis Res Ther. 2013;15(5):R112. [PMC3978948].

 

39.  Eckstein F, Hitzl W, Duryea J, Kwoh KC, Wirth W. Baseline and longitudinal change in isometric muscle strength prior to radiographic progression in osteoarthritic and pre-osteoarthritic knees - data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2013 May;21(5):682-690. Epub 2013 Mar 6.[PMC3624032].

 

40.  Eckstein F, Kwoh CK, Boudreau RM, Wang Z, Hannon MJ, Cotofana S, Hudelmaier MI, Wirth W, Guermazi A, Nevitt MC, John MR, Hunter DJ, for the OAI. Quantitative MRI measures of cartilage predict knee replacement: a case-control study from the Osteoarthritis Initiative. Ann Rheum Dis. 2013 Jun;72(6):924-9. Epub 2012 Jun 30.

 

41.  Felson DT, Niu J, Gross KD, Englund M, Sharma L, Cooke TD, Guermazi A, Roemer FW, Segal N, Goggins JM, Lewis CE, Eaton C, Nevitt MC. Valgus malalignment is a risk factor for lateral knee osteoarthritis incidence and progression: Findings from the multicenter osteoarthritis study and the osteoarthritis initiative. Arthritis Rheum. 2013; 65:355-362.[PMC3558618].

 

42.  Felson DT, Niu J, Yang T, Torner J, Lewis CE, Aliabadi P, Sack B, Sharma L, Guermazi A, Goggins J, Nevitt MC. Physical activity, alignment and knee osteoarthritis:  Data from MOST and the OAI. Osteoarthritis Cartilage. 2013;21(6):789-795.[PMC3648587].

 

43.  Felson D, Niu J, Sack B, Aliabadi P, McCullough C, Nevitt MC. Progression of osteoarthritis as a state of inertia. Ann Rheum Dis. 2013 Jun;72(6):924-9. Epub 2012 Jun 30.

 

44.  Hoogeboom TJ, den Broeder AA, de Bie RA, van den Ende CH. Longitudinal impact of joint pain comorbidity on quality of life and activity levels in knee osteoarthritis: data from the Osteoarthritis Initiative. Rheumatology (Oxford). 2013 Mar;52(3):543-6.[PMC3716330].

 

45.  Illingworth KD, El Bitar Y, Siewert K, Scaife SL, El-Amin S, Saleh KJ. Correlation of WOMAC and KOOS scores to tibiofemoral cartilage loss on plain radiography and 3 Tesla MRI: data from the osteoarthritis initiative. Knee Surg Sports Traumatol Arthrosc. Jan 23 2013. [Epub ahead of print].        

 

46.  Jungmann PM, Kraus MS, Alizai H, Nardo L, Baum T, Nevitt MC, McCulloch CE, Joseph GB, Lynch JA, Link TM. Association of metabolic risk factors with cartilage degradation assessed by t2 relaxation time at the knee: data from the osteoarthritis initiative. Arthritis Care Res (Hoboken). 2013 Dec;65(12):1942-50. Epub 2013 Aug 7.

 

47.  Jungmann PM, Kraus MS, Nardo L, Liebl H, Alizai H, Joseph GB, Liu F, Lynch J, McCulloch CE, Nevitt MC, Link TM. T2 relaxation time measurements are limited in monitoring progression, once advanced cartilage defects at the knee occur: Longitudinal data from the osteoarthritis initiative. J Magn Reson Imaging. 2013 Dec;38(6):1415-24. Epub 2013 Sep 13

 

48.  Jungmann PM, Tham SC, Liebl H, Nevitt MC, McCulloch CE, Lynch J, Link TM. Association of trochlear dysplasia with degenerative abnormalities in the knee: data from the Osteoarthritis Initiative. Skeletal Radiol. 2013 Oct;42(10):1383-1392. Epub 2013 Jun 26.[PMC3757255].

 

49.  Kahn TL, Soheili A, Schwarzkopf R. Outcomes of total knee arthroplasty in relation to preoperative patient-reported and radiographic measures: data from the osteoarthritis initiative. Geriatr Orthop Surg Rehabil. 2013 Dec;4(4):117-26. [PMC3943364].

 

50.  Kingsbury SR, Hensor EM, Walsh CA, Hochberg MC, Conaghan PG. How do people with knee osteoarthritis use osteoarthritis pain medications and does this change over time? Data from the Osteoarthritis Initiative. Arthritis Res Ther. 2013;15(5):R106.

 

51.  Lapane KL, Yang S, Jawahar R, McAlindon T, Eaton CB. CAM use among overweight and obese persons with radiographic knee osteoarthritis. BMC Complement Altern Med. 2013 Sep 28;13:241.[PMC3850510].

 

52.  Laslett LL, Kingsbury SR, Hensor EM, Bowes MA, Conaghan PG. Effect of bisphosphonate use in patients with symptomatic and radiographic knee osteoarthritis: data from the Osteoarthritis Initiative. Ann Rheum Dis. 2013 Apr 12. [Epub ahead of print].

 

53.  Lee J, Song J, Hootman JM, Semanik PA, Chang RW, Sharma L, Van Horn L, Bathon JM, Eaton CB, Hochberg MC, Jackson R, Kwoh CK, Mysiw WJ, Nevitt M, Dunlop DD. Obesity and other modifiable factors for physical inactivity measured by accelerometer in adults with knee osteoarthritis: Data from the osteoarthritis initiative (OAI). Arthritis Care Res (Hoboken). 2013;65:53-61.[PMC3449019].

 

54.  Lin W, Alizai H, Joseph GB, Srikhum W, Nevitt MC, Lynch JA, McCulloch CE, Link TM. Physical activity in relation to knee cartilage T2 progression measured with 3 T MRI over a period of 4 years: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2013 Oct;21(10):1558-66. Epub 2013 Jul 4.[ PMC3874212].

 

55.  Lu B, Ahmad O, Zhang FF, Driban JB, Duryea J, Lapane KL, McAlindon T, Eaton CB. Soft drink intake and progression of radiographic knee osteoarthritis: data from the osteoarthritis initiative. BMJ Open. 2013 Jul 19;3(7).[PMC3717463].

 

56.  Martel-Pelletier J, Roubille C, Abram F, Hochberg MC, Dorais M, Delorme P, Raynauld JP, Pelletier JP. First-line analysis of the effects of treatment on progression of structural changes in knee osteoarthritis over 24 months: data from the osteoarthritis initiative progression cohort. Ann Rheum Dis. 2013 Dec 13. [Epub ahead of print].

 

57.  Mercier C, Piperno M, Vignon E, Brandt K, Hochberg M, Hellio Le Graverand MP. In normal knees, joint space width (JSW) is correlated with the intermargin distance (IMD), a measure of medial tibial plateau alignment. Variations in IMD explain variability in JSW in serial radiographs. Joint Bone Spine. 2013 Mar;80(2):183-7. Epub 2012 Sep 19.

 

58.  Neogi T, Bowes M, Niu J, De Souza K, Vincent G, Goggins J, Zhang Y, Felson DT. MRI-based three-dimensional bone shape of the knee predicts onset of knee osteoarthritis: Data from the Osteoarthritis Initiative. Arthritis Rheum. 2013 Aug;65(8):2048-2058. Epub 2013 May 3.[PMC3729737].

 

59.  Pang J, Driban JB, Destenaves G, et al. Quantification of bone marrow lesion volume and volume change using semi-automated segmentation: data from the osteoarthritis initiative. BMC Musculoskelet Disord. Jan 2 2013;14:3.[PMC3637109].

 

60.  Rasanen LP, Mononen ME, Nieminen MT, Lammentausta E, Jurvelin JS, Korhonen RK, Investigators OAI. Implementation of subject-specific collagen architecture of cartilage into a 2D computational model of a knee joint-data from the osteoarthritis initiative (OAI). J Orthop Res. 2013;31:10-22.

 

61.  Riddle DL, Dumenci L. Self-rated health and symptomatic knee osteoarthritis over three years: Data from the osteoarthritis initiative. Arthritis Care Res (Hoboken). 2013 Feb;65(2):169-176.[PMC3386372].

 

62.  Riddle DL, Jensen MP. Construct and criterion-based validity of brief pain coping scales in persons with chronic knee osteoarthritis pain. Pain Med. 2013;14:265-275.[PMC3594566]

 

63.  Riddle DL, Jiranek WA, Hull JR. Validity and reliability of radiographic knee osteoarthritis measures by arthroplasty surgeons. Orthopedics. 2013;36:e25-32.

 

64.  Riddle DL, Moxley G, Dumenci L. Associations between statin use and changes in pain, function and structural progression: a longitudinal study of persons with knee osteoarthritis. Ann Rheum Dis. 2013;72:196-203.

 

65.  Riddle DL, Perera RA, Stratford PW, Jiranek WA, Dumenci L. Progressing toward and recovering from knee replacement surgery: A 5-year cohort study. Arthritis Rheum. 2013 Dec:65(12);3304-3313. Epub  2013 Aug 27.

 

66.  Riddle DL, Stratford PW. Body weight changes and corresponding changes in pain and function in persons with symptomatic knee osteoarthritis: a cohort study. Arthritis Care Res (Hoboken). 2013;65:15-22.[PMC3401342].

 

67.  Riddle DL, Stratford PW. Unilateral vs bilateral symptomatic knee osteoarthritis: associations between pain intensity and function.. Rheumatology (Oxford). 2013 Dec;52(12):2229-37. Epub 2013 Sep 11.[PMC3828512].

 

68.  Ruhdorfer A, Dannhauer T, Wirth W, Hitzl W, Kwoh CK, Guermazi A, Hunter DJ, Benichou O, Eckstein F. Thigh muscle cross-sectional areas and strength in advanced versus early painful osteoarthritis-An exploratory between-knee, within-person comparison in osteoarthritis initiative participants. Arthritis Care Res (Hoboken). 2013 Jul;65(7):1034-1042.

 

69.  Schneider E, Nessaiver M. The Osteoarthritis Initiative (OAI) magnetic resonance imaging quality assurance update. Osteoarthritis Cartilage. 2013:21:110-116.[PMC3629918].

 

70.  Song J, Hochberg MC, Chang RW, Hootman JM, Manheim LM, Lee J, Semanik PA, Sharma L, Dunlop DD.  Racial/ethnic differences in physical activity guideline attainment among participants in the osteoarthritis initiative.  Arthritis Care Res (Hoboken). 2013;65;195-202.[PMC3502693].

 

71.  Sun K, Song J, Lee J, Chang RW, Eaton CB, Ehrlich-Jones L, Kwoh KC, Manheim LM, Semanik PA, Sharma L, Sohn MW, Dunlop DD. Relationship of meeting physical activity guidelines with health-related utility. Arthritis Care Res (Hoboken). 2013 Dec 10. [Epub ahead of print].

 

72.  Urish KL, Williams AA, Durkin JR, Chu CR; the OAI Investigators Group. Registration of Magnetic Resonance Image Series for Knee Articular Cartilage Analysis: Data from the Osteoarthritis Initiative. Cartilage. 2013 Jan;4(1):20-27.[PMC3753048].

 

73.  Urish KL, Keffalas MG, Durkin JR, Miller DJ, Chu CR, Mosher TJ. T2 Texture Index of Cartilage Can Predict Early Symptomatic OA Progression: Data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2013 Oct:21(10):1550-1557. Epub 2013 Jun 15.[PMC3779506].

 

74.  Virayavanich W, Alizai H, Baum T, Nardo L, Nevitt MC, Lynch JA, McCulloch CE, Link TM. Association of frequent knee bending activity with focal knee lesions detected with 3T MRI - data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2013 Sep;65(9);1441-1448. Epub 2013 Apr 1.

 

75.  Wenger A, Wirth W, Hudelmaier M, Noebauer-Huhmann I, Trattnig S, Bloecker K, Frobell RB, Kwoh K, Eckstein F, Englund M. Meniscus body position, size and shape in persons with and without radiographic knee osteoarthritis: Quantitative analyses of knee MRIs from the Osteoarthritis Initiative. Arthritis Rheum. 2013 Jul;65(7);1804-1811. Epub Mar 25 2013.

 

76.  Wesseling J, Bierma-Zeinstra SM, Kloppenburg M, Meijer R, Bijlsma JW. Worsening of pain and function over 5 years in individuals with 'early' OA is related to structural damage: data from the Osteoarthritis Initiative and CHECK (Cohort Hip & Cohort Knee) study. Ann Rheum Dis. 2013 Nov 15. [Epub ahead of print].

 

77.  White DK, Niu J, Zhang Y. Is symptomatic knee osteoarthritis a risk factor for a trajectory    of fast decline in gait speed? Results from a longitudinal cohort study. Arthritis Care Res (Hoboken). 2013;65:187-194.[PMC3529801].

 

78.  Wirth W, Duryea J, Hellio Le Graverand MP, John MR, Nevitt M, Buck RJ, Eckstein F. Direct comparison of fixed flexion, radiography and MRI in knee osteoarthritis: responsiveness data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2013;21:117-125.[PMC3569717].

 

79.  Yamabe E, Ueno T, Miyagi R, Watanabe A, Guenzi C, Yoshioka H. Study of surgical indication for knee arthroplasty by cartilage analysis in three compartments using data from Osteoarthritis Initiative (OAI). BMC Musculoskelet Disord. 2013 Jun 25;14:194.[PMC3695763].

 

80.  Yang S, Dubé CE, Eaton CB, McAlindon TE, Lapane KL. Longitudinal use of complementary and alternative medicine among older adults with radiographic knee osteoarthritis. Clin Ther. 2013 Nov;35(11):1690-702. Epub 2013 Oct 18.[PMC3880574].

 

81.  Yerges-Armstrong L, Yau M, Liu Y, Krishnan S, Renner J, Eaton C, Kwoh C, Nevitt M, Duggan D, Mitchell B, Jordan J, Hochberg M, Jackson R. Association Analysis of BMD-associated SNPs with Knee Osteoarthritis. J Bone Miner Res. 2013 Dec 11. [Epub ahead of print].

 

2012

 

82.  Baum T, Joseph GB, Arulanandan A, Nardo L, Virayavanich W, Carballido-Gamio J, Nevitt MC, Lynch J, McCulloch CE, Link TM. Association of magnetic resonance imaging-based knee cartilage T2 measurements and focal knee lesions with knee pain: Data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2012;64:248-255.[PMC3267009].

 

83.  Baum T, Stehling C, Joseph GB, Carballido-Gamio J, Schwaiger BJ, Muller-Hocker C, Nevitt MC, Lynch J, McCulloch CE, Link TM. Changes in knee cartilage T2 values over 24 months in subjects with and without risk factors for knee osteoarthritis and their association with focal knee lesions at baseline: Data from the Osteoarthritis Initiative. J Magn Reson Imaging. 2012;35:370-378.[PMC3265616].

 

84.  Beattie KA, Macintyre NJ, Ramadan K, Inglis D, Maly MR. Longitudinal changes in intermuscular fat volume and quadriceps muscle volume in the thighs of women with knee osteoarthritis. Arthritis Care Res (Hoboken). 2012;64:22-29.[PMC3251718].

 

85.  Berger MJ, Kean CO, Goela A, Doherty TJ. Disease severity and knee extensor force in knee osteoarthritis: Data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2012;64:729-734.[PMC3335963].

 

86.  Bloecker K, Wirth W, Hudelmaier M, Burgkart R, Frobell R, Eckstein F. Morphometric Differences between the medial and lateral meniscus in healthy men - A three-dimensional analysis using magnetic sesonance imaging. Cells Tissues Organs. 2012;195:353-364.[PMC3696373].

 

87.  Colbert CJ, Song J, Dunlop D, Chmiel JS, Hayes KW, Cahue S, Moisio KC, Chang AH, Sharma L. Knee confidence as it relates to physical function outcome in persons with or at higher risk for knee osteoarthritis in the osteoarthritis. Arthritis Rheum. 2012;64:1437-1446.[PMC3319513].

 

88.  Cotofana S, Buck R, Wirth W, Roemer F, Duryea J, Nevitt M, Eckstein F. Cartilage thickening in early radiographic human knee osteoarthritis - within-person, between-knee comparison. Arthritis Care Res (Hoboken). 2012;64:1681-1690.[PMC3429643].

 

89.  Driban JB, Tassinari A, Lo GH, Price LL, Schneider E, Lynch JA, Eaton CB, McAlindon TE.  Bone marrow lesions are associated with altered trabecular morphometry. Osteoarthritis Cartilage. 2012;20:1519-152.[PMC3478500].

 

90.  Eckstein F, Mc Culloch CE, Lynch JA, Nevitt M, Kwoh CK, Maschek S, Hudelmaier M, Sharma L, Wirth W. How do short-term rates of femorotibial cartilage change compare to long-term changes? Four year follow-up data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2012 Nov;20(11):1250-1257.[PMCID: PMC3471368].

 

91.  Eckstein F, Wirth W, Nevitt MC. Recent advances in osteoarthritis imaging-the Osteoarthritis Initiative. Nat Rev Rheumatol. 2012;8;622-630.

 

92.  Guermazi A, Hunter DJ, Li L, Benichou O, Eckstein F, Kwoh CK, Nevitt M, Hayashi D. Different thresholds for detecting osteophytes and joint space narrowing exist between the site investigators and the centralized reader in a multicenter knee osteoarthritis study--data from the Osteoarthritis Initiative. Skeletal Radiol. 2012;41:179- 186.[PMC3181387].

 

93.  Haugen IK, Cotofana S, Englund M, Kvien TK, Dreher D, Nevitt M, Lane NE, Eckstein F, the Osteoarthritis Initiative. Hand joint space narrowing and osteophytes are associated with magnetic resonance imaging-defined knee cartilage thickness and radiographic knee osteoarthritis: Data from the Osteoarthritis Initiative. J Rheumatol. 2012;39:161-166.

 

94.  Hovis KK, Alizai H, Tham SC, Souza RB, Nevitt MC, McCulloch CE, Link TM. Non-traumatic anterior cruciate ligament abnormalities and their relationship to osteoarthritis using morphological grading and cartilage T2 relaxation times: data from the Osteoarthritis Initiative (OAI). Skeletal Radiol. 2012;41:1435-1443.[PMC3586320].

 

95.  Joseph GB, Baum T, Alizai H, Carballido-Gamio J, Nardo L, Virayavanich W, Lynch JA, Nevitt MC, McCulloch CE, Majumdar S, Link TM. Baseline mean and heterogeneity of MR cartilage T(2) are associated with morphologic degeneration of cartilage, meniscus, and bone marrow over 3years - data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2012;20;727-735.[PMC3595156]

 

96.  Laberge MA, Baum T, Virayavanich W, Nardo L, Nevitt MC, Lynch J, McCulloch CE, Link TM. Obesity increases the prevalence and severity of focal knee abnormalities diagnosed using 3T MRI in middle-aged subjects-data from the Osteoarthritis Initiative. Skeletal Radiol. 2012;41:633-641. 

 

97.  Lapane KL, Sands MR, Yang S, McAlindon TE, Eaton CB. Use of complementary and alternative medicine among patients with radiographic-confirmed knee osteoarthritis. Osteoarthritis Cartilage. 2012;20:22-28.[PMC3254852]. 

 

98.  Lester G. The Osteoarthritis Initiative: A NIH Public-Private Partnership. HSS J. 2012;8: 62-63.[PMC3295933].

 

99.  Lo GH, Tassinari A, Driban JB, Price LL, Schneider E, Majumdar S, McAlindon TE. Cross-sectional DXA and MR measures of tibial periarticular bone associate with radiographic knee osteoarthritis severity. Osteoarthritis Cartilage. 2012;20;686-693.[PMC3760173].

 

100. Mansournia MA, Danaei G, Forouzanfar MH, Mahmoodi M, Jamali M, Mansournia N, Mohammad K. Effect of physical activity on functional performance and knee pain in patients with osteoarthritis: Analysis with marginal structural models. Epidemiology. 2012;23:631-640.

 

101. Nardo L, Alizai H, Virayavanich W, Liu F, Hernandez A, Lynch JA, Nevitt MC, McCulloch CE, Lane NE, Link TM. Lumbosacral transitional vertebrae: association with low back pain.  Radiology. 2012;265:497-503.[PMC3480814].

 

102. Riddle DL. Validity of clinical measures of frontal plane knee alignment: Data from the Osteoarthritis Initiative. Man Ther. 2012;17:459-465.[PMC3423550].

 

103. Riddle DL, Jiranek WA, Neff RS, Whitaker D, Hull JR. Extent of tibiofemoral osteoarthritis before knee arthroplasty: multicenter data from the Osteoarthritis Initiative. Clin Orthop Relat Res. 2012;470: 2836-42.[PMC3442002].

 

104. Riddle DL, Kong X, Jiranek WA. Factors associated with rapid progression to knee arthroplasty: Complete analysis of three-year data from the osteoarthritis initiative. Joint Bone Spine. 2012;79:298-303.

 

105. Sattler M, Dannhauer T, Hudelmaier M, Wirth W, Sanger AM, Kwoh CK, Hunter DJ, Eckstein F. Side differences of thigh muscle cross-sectional areas and maximal isometric muscle force in bilateral knees with the same radiographic disease stage, but unilateral frequent Pain - Data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2012;20:532-540.[PMC3350840].

 

106. Schneider E, Nevitt M, McCulloch C, Cicuttini FM, Duryea J, Eckstein F, Tamez-Pena J. Equivalence and precision of knee cartilage morphometry between different segmentation teams, cartilage regions, and MR acquisitions. Osteoarthritis Cartilage. 2012;20:869-879.[PMC3391588].

 

107. Siorpaes K, Wenger A, Bloecker K, Wirth W, Hudelmaier M, Eckstein F. Interobserver reproducibility of quantitative meniscus analysis using coronal multiplanar DESS and IWTSE MR imaging. Magn Reson Med. 2012;67:1419-1426.[PMC3527078].

 

108. Stein V, Li L, Lo G, Guermazi A, Zhang Y, Kent Kwoh C, Eaton CB, Hunter DJ. Pattern of joint damage in persons with knee osteoarthritis and concomitant ACL tears. Rheumatol Int. 2012;32:1197-1208.[PMC3181385].

 

109. Tamez-Pena J, Farber J, Gonzalez P, Schreyer E, Schneider E, Totterman S. Unsupervised segmentation and quantification of anatomical knee features: Data from the Osteoarthritis Initiative. IEEE Trans Biomed Eng. 2012;59:1177-1186.

 

110. Wenger A, Englund M, Wirth W, Hudelmaier M, Kwoh K, Eckstein F, Investigators OAI. Relationship of 3D meniscal morphology and position with knee pain in subjects with knee osteoarthritis: a pilot study. Eur Radiol. 2012;22:211-220. 

 

111. Yang S, Jawahar R, McAlindon TE, Eaton CB, Lapane KL. Racial differences in symptom management approaches among persons with radiographic knee osteoarthritis. BMC Complement Altern Med. 2012;12:86.[PMC3493375].

 

2011

 

112. Ababneh SY, Prescott JW, Gurcan MN. Automatic graph-cut based segmentation of bones from knee magnetic resonance images for osteoarthritis research. Med Image Anal. 2011;15:438-448.[PMC3131695].

 

113. Bloecker K, Englund M, Wirth W, Hudelmaier M, Burgkart R, Frobell RB, Eckstein F. Size and position of the healthy meniscus, and its correlation with sex, height, weight, and bone area- a cross-sectional study. BMC Musculoskelet Disord.  2011;12:248.[PMC3215228].

 

114. Carballido-Gamio J, Joseph GB, Lynch JA, Link TM, Majumdar S. Longitudinal analysis of MRI T(2) knee cartilage laminar organization in a subset of patients from the osteoarthritis initiative: A texture approach. Magn Reson Med. 2011;65:1184-1194.

 

115. Carballido-Gamio J, Majumdar S. Atlas-based knee cartilage assessment. Magn Reson Med. 2011;66:575-581.[PMC3346276].

 

116. Clearfield J, Segal NA. Health Coverage and Its Relation to the Prevalence and Intensity of Symptomatic Knee Osteoarthritis. J Investig Med. 2011;59:956-960.[PMC3196827].

 

117. Dunlop DD, Song J, Semanik PA, Chang RW, Sharma L, Bathon JM, Eaton CB, Hochberg MC, Jackson RD, Kwoh CK, Mysiw WJ, Nevitt MC, Hootman JM. Objective physical activity measurement in the osteoarthritis initiative: Are guidelines being met? Arthritis Rheum. 2011;63:3372-3382.[PMC3205278].

 

118. Dunlop DD, Song J, Semanik PA, Sharma L, Chang RW. Physical activity levels and functional performance in the osteoarthritis initiative: a graded relationship. Arthritis Rheum. 2011;63:127-136.[PMC3010474].

 

119. Eckstein F, Cotofana S, Wirth W, Nevitt M, John MR, Dreher D, Frobell R, for the OAIiG. Greater rates of cartilage loss in painful knees than in pain-free knees after adjustment for radiographic disease stage: Data from the osteoarthritis initiative. Arthritis Rheum. 2011;63:2257-2267.[PMC3149734].

 

120. Hayashi D, Guermazi A, Kwoh CK, Hannon MJ, Moore C, Jakicic JM, Green SM, Roemer FW. Semiquantitative assessment of subchondral bone marrow edema-like lesions and subchondral cysts of the knee at 3T MRI: a comparison between intermediate-weighted fat-suppressed spin echo and Dual Echo Steady State sequences. BMC Musculoskelet Disord. 2011;12:198.[PMC3182962].

 

121. Hovis KK, Stehling C, Souza RB, Haughom BD, Baum T, Nevitt M, McCulloch C, Lynch JA, Link TM. Physical activity is associated with MR-based knee cartilage T2 measurements in asymptomatic subjects with and without osteoarthritis risk factors. Arthritis Rheum. 2011;63:2248-2256.[PMC3149726].

 

122. Iranpour-Boroujeni T, Watanabe A, Bashtar R, Yoshioka H, Duryea J. Quantification of cartilage loss in local regions of knee joints using semi-automated segmentation software: analysis of longitudinal data from the Osteoarthritis Initiative (OAI). Osteoarthritis Cartilage. 2011;19:309-314.[PMC3046247].

 

123. Joseph GB, Baum T, Carballido-Gamio J, Nardo L, Virayavanich W, Alizai H, Lynch JA, McCulloch CE, Majumdar S, Link TM. Texture analysis of cartilage T2 maps: individuals with risk factors for OA have higher and more heterogeneous knee cartilage MR T2 compared to normal controls - Data from the Osteoarthritis Initiative. Arthritis Res Ther. 2011;13:R153.[PMC3308083].

 

124. Knoop J, van der Leeden M, Thorstensson CA, Roorda LD, Lems WF, Knol DL, Steultjens MP, Dekker J. Identification of phenotypes with different clinical outcomes in knee osteoarthritis: Data from the osteoarthritis initiative. Arthritis Care Res (Hoboken). 2011;63:1535-1542.

 

125. Pan J, Pialat JB, Joseph T, Kuo D, Joseph GB, Nevitt MC, Link TM. Knee Cartilage T2 Characteristics and Evolution in Relation to Morphologic Abnormalities Detected at 3-T MR Imaging: A Longitudinal Study of the Normal Control Cohort from the Osteoarthritis Initiative. Radiology. 2011;261:507-515.[PMC3198219].

 

126. Pan J, Stehling C, Muller-Hocker C, Schwaiger BJ, Lynch J, McCulloch CE, Nevitt MC, Link TM. Vastus lateralis/vastus medialis cross-sectional area ratio impacts presence and degree of knee joint abnormalities and cartilage T2 determined with 3T MRI - an analysis from the incidence cohort of the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2011;19:65-73.[PMC3027210].

 

127. Prescott JW, Best TM, Swanson MS, Haq F, Jackson RD, Gurcan MN. Anatomically anchored tmplate-based level set segmentation: Application to quadriceps muscles in MR images from the Osteoarthritis Initiative. J Digit Imaging. 2011;24:28-43.[PMC2891211].

 

128. Reichmann WM, Katz JN, Losina E. Differences in self-reported health in the Osteoarthritis Initiative (OAI) and Third National Health and Nutrition Examination Survey (NHANES-III). PLoS One. 2011;6:e17345.[PMC3046148].

 

129. Riddle DL, Kong X, Fitzgerald GK. Psychological health impact on 2-year changes in pain and function in persons with knee pain: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2011;19:1095-1101.[PMC3159740].

 

130. Riddle DL, Stratford PW. Impact of pain reported during isometric quadriceps muscle strength testing in people with knee pain: data from the osteoarthritis initiative. Phys Ther. 2011;91:1478-1489.[PMC3185222].

 

131. Stehling C, Baum T, Mueller-Hoecker C, Liebl H, Carballido-Gamio J, Joseph GB, Majumdar S, Link TM. A novel fast knee cartilage segmentation technique for T(2) measurements at MR imaging - data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2011;19:984-989.

 

132. Tameem HZ, Ardekani S, Seeger L, Thompson P, Sinha US. Initial results on development and application of statistical atlas of femoral cartilage in osteoarthritis to determine sex differences in structure: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2011;34:372-383.[PMC3142327].

 

133. Wirth W, Buck R, Nevitt M, Hellio Le Graverand MP, Benichou O, Dreher D, Davies RY, Lee JH, Picha K, Gimona A, Maschek S, Hudelmaier M, Eckstein F. MRI-based extended ordered values more efficiently differentiate cartilage loss in knees with and without joint space narrowing than region-specific approaches using MRI or radiography - Data from the OA Initiative. Osteoarthritis Cartilage. 2011;19:689-699.[PMC3097310].

 

134.  Wirth W, Larroque S, Davies RY, Nevitt M, Gimona A, Baribaud F, Lee JH, Benichou O, Wyman BT, Hudelmaier M, Maschek S, Eckstein F, Group OAII. Comparison of 1-year vs 2-year change in regional cartilage thickness in osteoarthritis results from 346 participants from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2011;19:74-83.[PMC3046392].

 

135.  Zhang W, McWilliams DF, Ingham SL, Doherty SA, Muthuri S, Muir KR, Doherty M. Nottingham knee osteoarthritis risk prediction models. Rheum Dis. 2011;70:1599-1604.

 

2010

 

136.  Balamoody S, Williams TG, Waterton JC, Bowes M, Hodgson R, Taylor CJ, Hutchinson CE. Comparison of 3T MR scanners in regional cartilage thickness analysis in osteoarthritis: a cross-sectional multicentre multivendor study. Arthritis Res Ther. 2010;12:R202.[PMC2991039].

 

137.  Benichou OD, Hunter DJ, Nelson DR, Guermazi A, Eckstein F, Kwoh K, Myers SL, Wirth W, Duryea J, Osteoarthritis Initiative I. One-year change in radiographic joint space width in patients with unilateral joint space narrowing: data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2010;62:924-931.[PMC2927100].

 

138.  Bieleman HJ, Oosterveld FG, Oostveen JC, Reneman MF, Groothoff JW. Work participation and health status in early osteoarthritis of the hip and/or knee: a comparison between the Cohort Hip and Cohort Knee and the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2010;62:683-689.[PMC3005361].

 

139.  Bredbenner TL, Eliason TD, Potter RS, Mason RL, Havill LM, Nicolella DP. Statistical shape modeling describes variation in tibia and femur surface geometry between Control and Incidence groups from the osteoarthritis initiative database. J Biomech. 2010;43:1780-1786.[PMC2997679].

 

140.  Carballido-Gamio J, Blumenkrantz G, Lynch JA, Link TM, Majumdar S. Longitudinal analysis of MRI T(2) knee cartilage laminar organization in a subset of patients from the osteoarthritis initiative. Magn Reson Med. 2010;63:465-472.

 

141.  Chang A, Hochberg M, Song J, Dunlop D, Chmiel JS, Nevitt M, Hayes K, Eaton C, Bathon J, Jackson R, Kwoh CK, Sharma L. Frequency of varus and valgus thrust and factors associated with thrust presence in persons with or at higher risk of developing knee osteoarthritis. Arthritis Rheum. 2010;62:1403-1411.[PMC2921866].

 

142.  Dunlop DD, Semanik P, Song J, Sharma L, Nevitt M, Jackson R, Mysiw J, Chang RW, Osteoarthritis Initiative I. Moving to maintain function in knee osteoarthritis: evidence from the osteoarthritis initiative. Arch Phys Med Rehabil. 2010;91:714-721.[PMC2864942].

 

143.  Duryea J, Neumann G, Niu J, Totterman S, Tamez J, Dabrowski C, Le Graverand MP, Luchi M, Beals CR, Hunter DJ. Comparison of radiographic joint space width with magnetic resonance imaging cartilage morphometry: Analysis of longitudinal data from the osteoarthritis initiative. Arthritis Care Res (Hoboken). 2010;62:932-937.[PMC2937275].

 

144.  Eckstein F, Nevitt M, Gimona A, Picha K, Lee JH, Davies RY, Dreher D, Benichou O, Le Graverand MP, Hudelmaier M, Maschek S, Wirth W, for the OAIiG. Rates of change and sensitivity to change in cartilage morphology in healthy knees and in knees with mild, moderate, and end stage radiographic osteoarthritis. Arthritis Care Res (Hoboken). 2011 Mar;63(3):311-319. Epub 2010 Oct 18.[PMC3106126].

 

145.  Eckstein F, Wirth W, Hunter DJ, Guermazi A, Kwoh CK, Nelson DR, Benichou O, Investigators OAI. Magnitude and regional distribution of cartilage loss associated with grades of joint space narrowing in radiographic osteoarthritis--data from the Osteoarthritis Initiative (OAI). Osteoarthritis Cartilage. 2010;18:760-768.[PMC2975907].

 

146.  Eckstein F, Yang M, Guermazi A, Roemer FW, Hudelmaier M, Picha K, Baribaud F, Wirth W, Felson DT. Reference values and Z-scores for subregional femorotibial cartilage thickness--results from a large population-based sample (Framingham) and comparison with the non-exposed Osteoarthritis Initiative reference cohort. Osteoarthritis Cartilage. 2010;18:1275-1283.[PMC2982217].

 

147.  Elsner JJ, Portnoy S, Guilak F, Shterling A, Linder-Ganz E. MRI-based characterization of bone anatomy in the human knee for size matching of a medial meniscal implant. J Biomech Eng. 2010;132:101008.

 

148.  Felson DT, Lynch J, Guermazi A, Roemer FW, Niu J, McAlindon T, Nevitt MC. Comparison of BLOKS and WORMS scoring systems part II. Longitudinal assessment of knee MRIs for osteoarthritis and suggested approach based on their performance: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2010;18:1402-1407.[PMC3005331].

 

149.  Frobell RB, Nevitt MC, Hudelmaier M, Wirth W, Wyman BT, Benichou O, Dreher D, Davies R, Lee JH, Baribaud F, Gimona A, Eckstein F, Osteoarthritis Initiative I. Femorotibial subchondral bone area and regional cartilage thickness: a cross-sectional description in healthy reference cases and various radiographic stages of osteoarthritis in 1,003 knees from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2010;62:1612-1623.

 

150.  Frobell RB, Wirth W, Nevitt M, Wyman BT, Benichou O, Dreher D, Davies RY, Lee JH, Baribaud F, Gimona A, Hudelmaier M, Cotofana S, Eckstein F, investigators OAI. Presence, location, type and size of denuded areas of subchondral bone in the knee as a function of radiographic stage of OA - data from the OA initiative. Osteoarthritis Cartilage. 2010;18:668-676.[PMC3066411].

 

151.  Hunter DJ, Li L, Zhang YQ, Totterman S, Tamez J, Kwoh CK, Eaton CB, Le Graverand MP, Beals CR, Investigators OAI. Region of interest analysis: by selecting regions with denuded areas can we detect greater amounts of change? Osteoarthritis Cartilage. 2010;18:175-183.[PMC2818144].

 

152.  Lynch JA, Roemer FW, Nevitt MC, Felson DT, Niu J, Eaton CB, Guermazi A.  Comparison of BLOKS and WORMS scoring systems part I. Cross sectional comparison of methods to assess cartilage morphology, meniscal damage and bone marrow lesions on knee MRI: data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2010;18:1393-1401.[PMC3055245].

 

153.  Song J, Semanik P, Sharma L, Chang RW, Hochberg MC, Mysiw WJ, Bathon JM,   Eaton CB, Jackson R, Kwoh CK, Nevitt M, Dunlop DD. Assessing physical activity in persons with knee osteoarthritis using accelerometers: data from the osteoarthritis initiative. Arthritis Care Res (Hoboken). 2010;62:1724-1732.[PMC2995807].

 

154.  Stehling C, Lane NE, Nevitt MC, Lynch J, McCulloch CE, Link TM. Subjects with higher   physical activity levels have more severe focal knee lesions diagnosed with 3T MRI: analysis of a non-symptomatic cohort of the osteoarthritis initiative. Osteoarthritis Cartilage. 2010;18:776-786.

 

155.  Stehling C, Liebl H, Krug R, Lane NE, Nevitt MC, Lynch J, McCulloch CE, Link TM. Patellar cartilage: T2 values and morphologic abnormalities at 3.0-T MR imaging in relation to physical activity in asymptomatic subjects from the osteoarthritis initiative. Radiology. 2010;254:509-520.[PMC2809928].

 

156.  Stein V, Li L, Guermazi A, Zhang Y, Kent Kwoh C, Eaton CB, Hunter DJ, Investigators OAI. The relation of femoral notch stenosis to ACL tears in persons with knee osteoarthritis. Osteoarthritis Cartilage. 2010;18:192-199.

 

157.  Suri P, Morgenroth DC, Kwoh CK, Bean JF, Kalichman L, Hunter DJ. Low back pain and other musculoskeletal pain comorbidities in individuals with symptomatic osteoarthritis of the knee: data from the osteoarthritis initiative. Arthritis Care Res (Hoboken). 2010;62:1715-1723.[PMC2995827].

 

158.  Swanson MS, Prescott JW, Best TM, Powell K, Jackson RD, Haq F, Gurcan MN. Semi-automated segmentation to assess the lateral meniscus in normal and osteoarthritic knees. Osteoarthritis Cartilage. 2010;18:344-353.[PMC2826568].

 

159.  Thompson LR, Boudreau R, Newman AB, Hannon MJ, Chu CR, Nevitt MC, Kent Kwoh C, Investigators OAI. The association of osteoarthritis risk factors with localized, regional and diffuse knee pain. Osteoarthritis Cartilage. 2010;18:1244-1249.[PMC3132895].

 

160.  Vignon E, Brandt KD, Mercier C, Hochberg M, Hunter D, Mazzuca S, Powell K, Wyman B, Le Graverand MP. Alignment of the medial tibial plateau affects the rate of joint space narrowing in the osteoarthritic knee. Osteoarthritis Cartilage. 2010;18:1436-1440. [PMC3049986].

 

161.  Yin Y, Zhang X, Williams R, Wu X, Anderson DD, Sonka M. LOGISMOS--layered optimal graph image segmentation of multiple objects and surfaces: cartilage segmentation in the knee joint. IEEE Trans Med Imaging. 2010;29:2023-2037. [PMC3131162].

 

162.  Wirth W, Benichou O, Kwoh CK, Guermazi A, Hunter D, Putz R, Eckstein F, Investigators OAI. Spatial patterns of cartilage loss in the medial femoral condyle in osteoarthritic knees: data from the Osteoarthritis Initiative. Magn Reson Med. 2010;63:574-581.[PMC3132941].

 

163.  Wirth W, Nevitt M, Hellio Le Graverand MP, Benichou O, Dreher D, Davies RY, Lee J, Picha K, Gimona A, Maschek S, Hudelmaier M, Eckstein F, investigators OAI. Sensitivity to change of cartilage morphometry using coronal FLASH, sagittal DESS, and coronal MPR DESS protocols--comparative data from the Osteoarthritis Initiative (OAI). Osteoarthritis Cartilage. 2010;18:547-554.[PMC2846231].

 

2009

 

164.  Bae KT, Shim H, Tao C, Chang S, Wang JH, Boudreau R, Kwoh CK. Intra- and inter-observer reproducibility of volume measurement of knee cartilage segmented from the OAI MR image set using a novel semi-automated segmentation method. Osteoarthritis Cartilage. 2009;17:1589-1597.[PMC2941641].

 

165.  Brem MH, Lang PK, Neumann G, Schlechtweg PM, Schneider E, Jackson R, Yu J, Eaton CB, Hennig FF, Yoshioka H, Pappas G, Duryea J. Magnetic resonance image segmentation using semi-automated software for quantification of knee articular cartilage---initial evaluation of a technique for paired scans. Skeletal Radiol. 2009;38:505-511.[PMC3018074].

 

166.  Eckstein F, Benichou O, Wirth W, Nelson DR, Maschek S, Hudelmaier M, Kwoh CK, Guermazi A, Hunter D, Osteoarthritis Initiative I. Magnetic resonance imaging-based cartilage loss in painful contralateral knees with and without radiographic joint space narrowing: Data from the osteoarthritis initiative. Arthritis Rheum. 2009;61:1218-1225.[PMC2935616].

 

167.  Eckstein F, Maschek S, Wirth W, Hudelmaier M, Hitzl W, Wyman B, Nevitt M, Le Graverand MP. One year change of knee cartilage morphology in the first release of participants from the Osteoarthritis Initiative progression subcohort: association with sex, body mass index, symptoms and radiographic osteoarthritis status. Ann Rheum Dis. 2009;68:674-679.[PMC2976866].

 

168.  Eckstein F, Wirth W, Hudelmaier MI, Maschek S, Hitzl W, Wyman BT, Nevitt M, Hellio Le Graverand MP, Hunter D, Group OAII. Relationship of compartment-specific structural knee status at baseline with change in cartilage morphology: a prospective observational study using data from the osteoarthritis initiative. Arthritis Res Ther. 2009;11:R90.[PMC2714146].

 

169.  Felson DT, Cooke TD, Niu J, Goggins J, Choi J, Yu J, Nevitt MC, Group OAII. Can anatomic alignment measured from a knee radiograph substitute for mechanical alignment from full limb films? Osteoarthritis Cartilage. 2009;17:1448-1452.[PMC2763977].

 

170.  Hunter DJ, Niu J, Zhang Y, Totterman S, Tamez J, Dabrowski C, Davies R, Le Graverand MP, Luchi M, Tymofyeyev Y, Beals CR. Change in cartilage morphometry: a sample of the progression cohort of the Osteoarthritis Initiative. Ann Rheum Dis. 2009;68:349-356.[PMC2734969].

 

171.  Lo GH, Hunter DJ, Nevitt M, Lynch J, McAlindon TE, Group OAII. Strong association of MRI meniscal derangement and bone marrow lesions in knee osteoarthritis: data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2009;17:743-747.[PMC2771759].

 

172.  Lo GH, McAlindon TE, Niu J, Zhang Y, Beals C, Dabrowski C, Le Graverand MP, Hunter DJ, Group OAII. Bone marrow lesions and joint effusion are strongly and independently associated with weight-bearing pain in knee osteoarthritis: data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2009;17:1562-1569.[PMC2787856].

 

173.  Prescott JW, Priddy M, Best TM, Pennell M, Swanson MS, Haq F, Jackson RD, Gurcan MN. An automated method to detect interstitial adipose tissue in thigh muscles for patients with osteoarthritis. Conf Proc IEEE Eng Med Biol Soc. 2009;1:6360-6363.[PMC2826818].

 

174.  Riddle DL, Kong X, Jiranek WA. Two-year incidence and predictors of future knee arthroplasty in persons with symptomatic knee osteoarthritis: preliminary analysis of longitudinal data from the osteoarthritis initiative. Knee. 2009;16:494-500.[PMC2801437].

 

175.  Shim H, Chang S, Tao C, Wang JH, Kwoh CK, Bae KT. Knee cartilage: efficient and reproducible segmentation on high-spatial-resolution MR images with the semiautomated graph-cut algorithm method. Radiology. 2009;251:548-556.

 

176.  Thompson LR, Boudreau R, Hannon MJ, Newman AB, Chu CR, Jansen M, Nevitt MC, Kwoh CK, Osteoarthritis Initiative I. The knee pain map: reliability of a method to identify knee pain location and pattern. Arthritis Rheum. 2009;61:725-731.[PMC2802101].

 

177.   Wesseling J, Dekker J, van den Berg WB, Bierma-Zeinstra SM, Boers M, Cats HA, Deckers P, Gorter KJ, Heuts PH, Hilberdink WK, Kloppenburg M, Nelissen RG, Oosterveld FG, Oostveen JC, Roorda LD, Viergever MA, ten Wolde S, Lafeber FP, Bijlsma JW. CHECK (Cohort Hip and Cohort Knee): similarities and differences with the Osteoarthritis Initiative. Ann Rheum Dis. 2009;68:1413-1419. [PMC3134276].

 

178.  Wirth W, Hellio Le Graverand MP, Wyman BT, Maschek S, Hudelmaier M, Hitzl W, Nevitt M, Eckstein F, Group OAII. Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort. Osteoarthritis Cartilage. 2009;17:291-297.[PMC2778007].

 

2008

 

179.  Lester G. Clinical research in OA - the NIH Osteoarthritis Initiative. J Musculoskelet Neuronal Interact. 2008;8:313-314.

 

180.  Peterfy CG, Schneider E, Nevitt M. The osteoarthritis initiative: report on the design rationale for the magnetic resonance imaging protocol for the knee. Osteoarthritis Cartilage. 2008;16:1433-1441.[PMC3048821].

 

181.  Schneider E, NessAiver M, White D, Purdy D, Martin L, Fanella L, Davis D, Vignone M, Wu G, Gullapalli R. The osteoarthritis initiative (OAI) magnetic resonance imaging quality assurance methods and results. Osteoarthritis Cartilage. 2008;16:994-1004.[PMC2584336].

 

182.  Watt E, Bui AA. Evaluation of a dynamic bayesian belief network to predict osteoarthritic knee pain using data from the osteoarthritis initiative. AMIA Annu Symp Proc. 2008:788-792.[PMC2656041].

 

2007

 

183.  Duryea J, Neumann G, Brem MH, Koh W, Noorbakhsh F, Jackson RD, Yu J, Eaton CB, Lang P. Novel fast semi-automated software to segment cartilage for knee MR acquisitions. Osteoarthritis Cartilage. 2007;15:487-492.

 

184.  Eckstein F, Kunz M, Hudelmaier M, Jackson R, Yu J, Eaton CB, Schneider E. Impact of coil design on the contrast-to-noise ratio, precision, and consistency of quantitative cartilage morphometry at 3 Tesla: a pilot study for the osteoarthritis initiative. Magn Reson Med. 2007;57:448-454.

 

185.  Eckstein F, Kunz M, Schutzer M, Hudelmaier M, Jackson RD, Yu J, Eaton CB, Schneider E. Two year longitudinal change and test-retest-precision of knee cartilage morphology in a pilot study for the osteoarthritis initiative. Osteoarthritis Cartilage. 2007;15:1326-1332.[PMC2704340].

 

186.  Eckstein F, Mosher T, Hunter D. Imaging of knee osteoarthritis: data beyond the beauty. Curr Opin Rheumatol. 2007;19:435-443.

 

2006

 

187.  Eckstein F, Hudelmaier M, Wirth W, Kiefer B, Jackson R, Yu J, Eaton CB, Schneider E. Double echo steady state magnetic resonance imaging of knee articular cartilage at 3 Tesla: a pilot study for the Osteoarthritis Initiative. Ann Rheum Dis. 2006;65:433-441.[PMC1798091].

 

2004

 

188.  Eaton CB. Obesity as a risk factor for osteoarthritis: mechanical versus metabolic. Med Health R I. 2004;87:201-204.

 

189.  Fawaz-Estrup F. The osteoarthritis initiative: an overview. Med Health R I. 2004;87:169-171.

 

190.  Felson DT, Nevitt MC. Epidemiologic studies for osteoarthritis: new versus conventional study design approaches. Rheum Dis Clin North Am. 2004;30:783-797, vii.

 

2003

 

191.  McGowan JA. Perspectives on the future of bone and joint diseases. J Rheumatol    Suppl. 2003;67:62-64.

 

 

Articles reviewing OAI findings

 

2014

 

1.    Baum T, Joseph GB, Karampinos DC, Jungmann PM, Link TM, Bauer JS.Cartilage and meniscal T2 relaxation time as non-invasive biomarker for knee osteoarthritis and cartilage repair procedures. Osteoarthritis Cartilage. 2013 Oct;21(10):1474-84. Epub 2013 Jul 27. Review. [PMC3929642].

 

2.    Eckstein F, Kwoh CK, Link TM; for the OAI investigators. Imaging research results from the Osteoarthritis Initiative (OAI): a review and lessons learned 10 years after start of enrolment. Ann Rheum Dis. 2014 Apr 19. [Epub ahead of print].

 

3.    Pelletier JP, Cooper C, Peterfy C, Reginster JY, Brandi ML, Bruyère O, Chapurlat R, Cicuttini F, Conaghan PG, Doherty M, Genant H, Giacovelli G, Hochberg MC, Hunter DJ, Kanis JA, Kloppenburg M, Laredo JD, McAlindon T, Nevitt M, Raynauld JP, Rizzoli R, Zilkens C, Roemer FW, Martel-Pelletier J, Guermazi A. What is the predictive value of MRI for the occurrence of knee replacement surgery in knee osteoarthritis?  Ann Rheum Dis. 2013 Oct;72(10):1594-604. Epub 2013 Jul 25. Review.

 

2013

 

4.    Li X, Majumdar S. Quantitative MRI of articular cartilage and its clinical applications. J Magn Reson Imaging. 2013 Nov;38(5):991-1008. Epub 2013 Oct 2. [PMC3858854].

 

2012

 

5.    Eckstein F, Wirth W, Nevitt MC. Recent advances in osteoarthritis imaging-the Osteoarthritis Initiative. Nat Rev Rheumatol. 2012;8;622-630.